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FLASH GENE

Symbol

PGLYRP2

contributors: - updated : 30-05-2007

HGNC name	peptidoglycan recognition protein 2
HGNC id	10495

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19p13.12      Physical location : 15.579.458 - 15.590.315
Synonym name	peptidoglycan recognition protein-like
	N-acetylmuramoyl-l-alanine amidase
Synonym symbol(s)	PGRPL, PGRP-L, PGLYRPL, HMFT0141 TAGL-like, tagl-beta, tagL-alpha, NAMLAA
EC.number	3.5.1.28

DNA

TYPE	functioning gene
SPECIAL FEATURE	arranged in tandem
STRUCTURE	10.00 kb     4 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver         Reproductive female system breast mammary gland       male system testis

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / hematopoietic bone marrow

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	an N-terminal signal peptide
	2 transmembrane segments
	an extracellular C terminus containing PGRP domains III, II, and I

HOMOLOGY

Homologene

FAMILY

n-acetylmuramoyl-l-alanine amidase 2 family

CATEGORY

enzyme , immunity/defense

SUBCELLULAR LOCALIZATION	extracellular
	plasma membrane
	intracellular
	intracellular,cytoplasm,cytosolic,granule

basic FUNCTION	binds specifically to peptidoglycan and is involved in innate immunity
	having N-acetylmuramoyl-l-alanine amidase activity

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS