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FLASH GENE
Symbol PFN4 contributors: - updated : 18-11-2005
HGNC name profilin family, member 4
HGNC id 31103
Location 2p23.3      Physical location : 24.338.243 - 24.346.151
DNA
TYPE functioning gene
STRUCTURE 7.00 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  predominantly
Reproductivemale systemtestis  highly
 male systemprostate  moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to rattus Pfn4
ortholog to murine Pfn4
Homologene
FAMILY
  • profilin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton
    basic FUNCTION
  • affecting the structure of the cytoskeleton
  • involved in actin cytoskeleton organization and biogenesis
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • actin
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS