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FLASH GENE
Symbol PEX11G contributors: npt/ - updated : 15-03-2006
HGNC name peroxisomal biogenesis factor 11 gamma
HGNC id 20208
Location 19p13.2      Physical location : 7.541.760 - 7.553.905
Synonym name
  • peroxin Pex11p gamma
  • peroxisomal biogenesis factor 11C
  • peroxin-11C
  • Synonym symbol(s) MGC4281, PEX11C
    DNA
    TYPE functioning gene
    STRUCTURE 12.15 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    EMR4 19p13.3 egf-like module containing, mucin-like, hormone receptor-like 4 LOC284428 19p13.3 similar to methyl-CpG binding domain protein 3-like 2 MBD3L2 19p13.3 methyl-CpG binding domain protein 3-like 2 LOC388498 19 similar to methyl-CpG binding domain protein 3-like 2 MGC4054 19p13.3 hypothetical protein MGC4054 INSR 19p13.3-p13.2 insulin receptor P114-RHO-GEF 19p13.3 insulin receptor PEX11G 19p13.2 peroxisomal biogenesis factor 11 gamma FLJ35784 19p13.3 FLJ35784 protein ZNF358 19p13.3 zinc finger protein 358 MCOLN1 19p13.3-13.2 mucolipin 1 NTE 19p13.3-p13.2 mucolipin 1 KIAA1543 19p13.3-p13.2 mucolipin 1 XAB2 19p13.3 XPA binding protein 2 MGC41903 STXBP2 19p13.3-p13.2 syntaxin binding protein 2 RETN 19p13.3 resistin LOC199675 19p13.3 hypothetical protein LOC199675 TRAPPC5 19p13.3 trafficking protein particle complex 5 FCER2 19p13.3 Fc fragment of IgE, low affinity II, receptor for (CD23A) UNQ431 19p13.3 DTTR431 CD209 19p13 CD209 antigen CD209L 19p13.3 CD209 antigen-like LOC390879 19 similar to DTTR431 LOC115704 19p13.3 similar to ecotropic viral integration site 5; Neuroblastoma stage 4S gene LOC388499 19 similar to lysophospholipase II; acyl-protein thioesterase FLJ23420 19p13.3 hypothetical protein FLJ23420 MAP2K7 19p13.2 mitogen-activated protein kinase kinase 7 LOC388500 19 LOC388500 SNAPC2 19q13.3-p13.2 small nuclear RNA activating complex, polypeptide 2, 45kDa TIMM44 19p13.3-p13.2 translocase of inner mitochondrial membrane 44 homolog (yeast) ELAVL1 19p13.2 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1143 - 241 - -
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon  
     pancreas exocrine    
     stomach   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two putative transmembrane segments, showing 22p100 and 23p100 AAs identity to PEX11A and PEX11B (Tanaka 2003)
  • HOMOLOGY
    Homologene
    FAMILY
  • peroxin-11 family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,peroxisome
    text peroxisomal membrane protein
    basic FUNCTION
  • may play a role in peroxisome homeostasis such as regulation of organelle abundance
  • may alos be involved in peroxisome proliferation
  • phosphorylation-dependent activation of peroxisome proliferator protein PEX11G controls peroxisome abundance (Knoblach 2010)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS