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FLASH GENE
Symbol PDXK contributors: np - updated : 07-12-2004
HGNC name pyridoxal (pyridoxine, vitamin B6) kinase
HGNC id 8819
Location 21q22.3      Physical location : 45.138.977 - 45.182.187
Synonym name
  • chromosome 21 open reading frame 97
  • pyridoxine kinase
  • chromosome 21 open reading frame 124
  • vitamin B6 kinase
  • pyridoxamine kinase
    • Synonym symbol(s) PKH, PNK, C21orf97, C21orf124, FLJ21324, PRED79, FLJ31940, MGC15873
    EC.number 2.7.1.35
    DNA
    TYPE functioning gene
    STRUCTURE 43.00 kb     11 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 7390 35 312 - -
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines breast cancer, invasive tumor, hepatocellular carcinoma
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to murine Pdxk
    homolog to C.elegans f57c9.1
    Homologene
    FAMILY
  • carbohydrate kinase family
  • pyridoxine kinase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION pyridoxal kinase
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism vitamin
    signaling
    a component
  • synthesizing pyridoxal-5-phosphate from vitamin b6
    • INTERACTION
    DNA
    RNA
    small molecule
    ATP
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS