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FLASH GENE
Symbol PDE1C contributors: - updated : 27-09-2004
HGNC name phosphodiesterase 1C, calmodulin-dependent 70kDa
HGNC id 8776
Location 7p15.3      Physical location : 31.792.631 - 32.338.383
Synonym name
  • phosphodiesterase 1C, calmodulin-dependent (70kD)
  • Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A)
  • Synonym symbol(s) HCAM3
    EC.number 3.1.4.17
    DNA
    TYPE functioning gene
    STRUCTURE 281.00 kb     18 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    CRHR2 7p21-p15 corticotropin releasing hormone receptor 2 ADCYAP1R1 7p14 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I INMT 7p15.3-p15.2 indolethylamine N-methyltransferase FLJ22374 7p15.1 hypothetical protein FLJ22374 PODXL 7q32-q33 podocalyxin-like AQP1 7p14 aquaporin 1 (channel-forming integral protein, 28kDa) LOC392793 7 similar to eukaryotic translation elongation factor 1 beta 2; eukaryotic translation elongation factor 1 beta 1 LOC392988 7 similar to ribosomal protein S14 GHRHR 7p14 growth hormone releasing hormone receptor NEUROD6 7p15.3 neurogenic differentiation 6 ADCYAP1R1 7p14 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I LOC223075 7p15.1 hypothetical protein LOC223075 NEUROD6 7p15.3 neurogenic differentiation 6 C7orf16 7p15 chromosome 7 open reading frame 16 PLXNA4 7q32.3 plexin A4 PDE1C 7p15.3 phosphodiesterase 1C, calmodulin-dependent 70kDa LOC223075 7p15.1 hypothetical protein LOC223075 C7orf16 7p15 chromosome 7 open reading frame 16 DKFZp434G0625 7q32.3 hypothetical protein DKFZp434G0625 PDE1C 7p15.3 phosphodiesterase 1C, calmodulin-dependent 70kDa FLJ40288 7q32.3 hypothetical protein FLJ40288 FLJ20420 LOC392882 7 similar to PRPS2 protein LOC392883 7 similar to ADP,ATP carrier protein, fibroblast isoform (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) LSM5 7p14.3 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) KIAA0241 7p14.3 KIAA0241 protein LOC89231 7p14.3 LOC89231 LOC392989 7 hypothetical gene supported by AK130770; NM_003932 LOC392012 7 similar to PRPS2 protein LOC392013 7 similar to ADP,ATP carrier protein, fibroblast isoform (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) LSM5 7p14.3 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) KIAA0241 7p14.3 KIAA0241 protein KBTBD2 7p14.3 kelch repeat and BTB (POZ) domain containing 2 SEC8 LOC392652 7 similar to Retinitis pigmentosa 9 protein (Pim-1 associated protein) (PAP-1) FKBP9 7p11.1 FK506 binding protein 9, 63 kDa LOC89231 7p14.3 LOC89231 NT5C3 7p14.3 5'-nucleotidase, cytosolic III LOC222136 B1 7p14 parathyroid hormone-responsive B1 gene
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 5.6 80 709 heart, brain bughney
    - - 10 - 634 heart, brain and lung lowly bughney
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Nervousbrain    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to murine Pde1c
    Homologene
    FAMILY cyclic nucleotide phosphodiesterase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS