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FLASH GENE
Symbol PDCD7 contributors: - updated : 16-12-2004
HGNC name programmed cell death 7
HGNC id 8767
Location 15q22.2      Physical location : 65.409.717 - 65.426.174
Synonym name apoptosis-related protein ES18
Synonym symbol(s) ES18, HES18, MGC22015
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
FLJ22875 15q22.1 hypothetical protein FLJ22875 SNX1 15q22-q23 sorting nexin 1 SNX22 20q12-13.1 sorting nexin 22 PPIB 15q21-q22 peptidylprolyl isomerase B (cyclophilin B) CSNK1G1 15q22.1-q22.31 casein kinase 1, gamma 1 KIAA0101 15q22.1 casein kinase 1, gamma 1 TRIP4 15q22.1 thyroid hormone receptor interactor 4 KIAA0295 15q21.3-q22.1 thyroid hormone receptor interactor 4 OAZ2 15q22 ornithine decarboxylase antizyme 2 RBPMS2 15q22.1 RNA-binding protein with multiple splicing 2 FLJ22692 15q22.1 hypothetical protein FLJ22692 pp9099 15q22.1 PH domain-containing protein LOC348094 15q22.2 hypothetical protein LOC348094 ACP33 15q21-q22 hypothetical protein LOC348094 MtFMT 15q22.2 methionyl-tRNA formyltransferase, mitochondrial OSTbeta 15q22.2 organic solute transporter beta RIS LOC390594 15 similar to RIKEN cDNA C230080I20 gene LOC390595 15 similar to ubiquitin associated protein PDCD7 15q22.2 programmed cell death 7 CLPX 15q22.31 ClpX caseinolytic protease X homolog (E. coli) CILP 15q22 cartilage intermediate layer protein, nucleotide pyrophosphohydrolase FLJ20509 15q22.2 hypothetical protein FLJ20509 LOC390596 15 similar to cell division cycle 2-like 1 (PITSLRE proteins) isoform 1; cell division cycle 2-like 1; PITSLRE protein kinase alpha; p58/GTA protein kinase; galactosyltransferase associated protein kinase; CDC-related protein kinase p5 PUNC 15q22.3-q23 putative neuronal cell adhesion molecule NOPE 15q22.2 putative neuronal cell adhesion molecule DPP8 15q22 dipeptidylpeptidase 8 HSPC121 15q22.2 butyrate-induced transcript 1 DKFZP564O1664 15q22.2 hypothetical protein DKFZp564O1664 SLC24A1 15q22 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 IRLB 15q22.2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 LOC388127 15 similar to Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing protein) (Single-strand binding protein) (hnRNP core protein A1) (HDP) RAB11A 15q21.3-q22.31 RAB11A, member RAS oncogene family MEGF11 15q22.2 MEGF11 protein
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node    
 thymus    
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a proline-rich N terminus
  • acidic regions with high contents of glutamic acid
  • C-terminal half having several alpha-helix regions, evenly spaced leucines and hydrophobic amino acids
  • LxxLL transcriptional coactivator signature motif
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION involved in specific apoptotic processes in T-cells
    CELLULAR PROCESS cell life, cell death/apoptosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS