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FLASH GENE
Symbol PCTK3 contributors: - updated : 28-12-2005
HGNC name PCTAIRE protein kinase 3
HGNC id 8751
Location 1q31-q32      Physical location : -
Synonym symbol(s) PCTAIRE, PCTAIRE3
EC.number 2.7.1.37
DNA
TYPE functioning gene
STRUCTURE 28.00 kb     16 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3165 - 504 limited to several subcortical nuclei of the basal gangli and the spinal cord Herskovits
an insert that adds 90 nucleotides to the third exon
- - 3075 - 474 throughout the brain and in the majority of tissues analyzed Herskovits
- - 3157 - 474 - Herskovits
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Nervousbrain    
Reproductivefemale systemovary  highly
Urinarybladder   highly
Visualeye    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • serine/threonine kinase
  • the PCTAIRE motif
    • HOMOLOGY
    interspecies homolog to cdc2
    Homologene
    FAMILY PCTAIRE subfamily of CDC2-related serine/threonine protein kinases
    CATEGORY enzyme , receptor membrane serine/threonine kinase
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,nucleus
    basic FUNCTION
  • may play a role in signal transduction cascades in terminally differentiated cells
    • CELLULAR PROCESS cell cycle
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS