basic FUNCTION
| involved in the development of the central nervous system |
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may play a role in the pathophysiology of Alzheimer disease and Huntington disease through a mechanism of calcium/calmodulin disregulation  |
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has the potential to alter the Ca2+-binding dynamics of free CALM1 and CALM1 that is bound to other target proteins  |
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with NRGN, small IQ-motif calmodulin (CALM1)-binding proteins originally identified in the central nervous system  |
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can bind to either apo- or Ca2+-CALM1, and can modulate Ca2+ binding to the C-domain of CALM1  |
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neurospecific, small calmodulin-binding protein that binds both calcium-free and calcium-binding calmodulin to regulate the calmodulin-mediated signal  |
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promotes neuroendocrine cell differentiation and neurotransmitter release by activating calmodulin function  |
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modulates the kinetics of Ca2+ binding to CALM1, and regulating ligand-induced Ca2+ release gives PCP4 the potential to broadly affect cell signaling  |
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is a modulator of Ca(2+)-Calmodulin signaling  |
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contributes significantly to the development of Down syndrome phenotypes through molecular and functional changes  |
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is a regulator of aldosterone production in normal, hyperplastic, and neoplastic human adrenocortical cells  |