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Symbol PCDHG@ contributors: npt - updated : 16/10/2008
HGNC name protocadherin gamma cluster
HGNC id 8695
Location 5q31.3      Physical location : -
Synonym name protocadherin, cadherin-related neuronal receptor,gamma cluster, organized as the Ig or TCR gene clusters, including 24 variable genes and pseudogenes divided in three subfamilies :
  • subfamily A : twelve genes PCDHGA to PCDHGA12
  • subfamily B : twelve genes PCDHGB1 to PCDHGB7 and two pseudogenes PCDHGB8, PCDHGB9P
  • subfamily C : three genes PCDHGC3 to PCDHGC5
    • Synonym symbol(s) PCDHVG@, PCDH2, PCDH4, PCDHG
    DNA
    TYPE cluster
    SPECIAL FEATURE arranged in tandem
    text one of the three protocadherin clustersarranged in tandem
    MAPPING cloned Y linked   status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • six extracellular cadherin repeats
  • a transmembrane segment, joining a unique C terminal segment to complete the molecule
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • cadherin superfamily of calcium dependent cell-cell adhesion glycoproteins
    • CATEGORY
    SUBCELLULAR LOCALIZATION     plasma membrane,junction
    text localized at the synaptic junction
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS