| basic FUNCTION
| cofactor necessary for ligand transactivation by nuclear hormone receptors |
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involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) |
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suppresses tumorigenesis, at least in part, through its ability to regulate CDKN1A  |
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with CHD7, during neural crest (NC) formation synergistically regulate activity of distal genomic elements that control the expression of critical NC transcription factors, in turn allowing for transcriptional reprogramming, acquisition of multipotency and migratory potential |
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BRD7 and PBRM1 are unique regulators of replicative senescence in human cells |
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repressor of IL10 transcription in Th2 cells, suggesting that the differential recruitment of different SWI/SNF subtypes can have direct consequences on chromatin structure and gene transcription) |
