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FLASH GENE
Symbol PART1 contributors: mct/npt - updated : 24/09/2008
Location 5q12.1      Physical location : 59.783.539 - 59.843.484
Genatlas name prostate androgen-regulated transcript 1
Synonym name prostate-specific and androgen-regulated protein 1
Synonym symbol(s) DKFZP586D0823, PART-1
DNA
TYPE like-sequence
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
text structure binding site for PBX1A
MAPPING cloned Y linked N status provisional
Physical map
MAP3K1 5q11.2 mitogen-activated protein kinase kinase kinase 1 MGC33648 5q11.2 hypothetical protein MGC33648 FLJ35954 5q11.2 hypothetical protein FLJ35954 DKFZp761C169 5q11.2 vasculin LOC133374 5q11.2 similar to hypothetical protein FLJ10534 LOC391787 5 similar to sal-like 4 LOC345651 5q12.1 similar to RIKEN cDNA 4732495G21 gene SNK 5q12.1-q13.2 serum-inducible kinase FLJ33641 5q12.1 hypothetical protein FLJ33641 RAB3C 5q13 RAB3C, member RAS oncogene family PDE4D 5q12 phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) LOC391788 5 similar to PDE4D protein LOC389291 5 similar to cAMP-specific phosphodiesterase PDE4D7 LOC391789 5 similar to ribosomal protein L31 LOC345659 5q12.1 similar to template acyivating factor-I alpha PART1 5q12.1 similar to template acyivating factor-I alpha XTP1 5q12.1 HBxAg transactivated protein 1 LOC391790 5 similar to KRT8 protein FLJ23563 5q12.1 hypothetical protein FLJ23563 CKN1 5q11.1-q11.2 Cockayne syndrome 1 (classical) FLJ12595 5q12.1 hypothetical protein FLJ12595 LOC91942 5q12.1 hypothetical protein LOC91942 LOC389292 5 LOC389292 LOC57399 5q12.1 uncharacterized gastric protein ZA52P ZSWIM6 5q12.1 zinc finger, SWIM domain containing 6 FLJ37543 5q12.1-q12.2 hypothetical protein FLJ37543 KIF2 5q12-q13 kinesin heavy chain member 2 HSA9761 5q11-q14 putative dimethyladenosine transferase IPO11 5q12.1 importin 11 LOC246715 5q12.2 cell division control protein CKS1 pseudogene SLRN 5q12.1 synleurin LOC389293 5 similar to hypothetical protein HTR1A 5q11.2-q13 5-hydroxytryptamine (serotonin) receptor 1A
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticthymus    
Digestiveintestinelarge intestinecolon  
 salivary gland    
Reproductivefemale systembreast   
 male systemprostate  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
Lymphoid    
nervousdorsal root ganglia   
cells
SystemCellPubmedSpeciesStageRna symbol
Endocrineislet cell (alpha,beta...)
cell lineage
cell lines androgen resistant prostate, breast cancer
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • motifs for myristoylation and phosphorylation by protein kinase C
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by progestins estrogens and glucocorticoid
    induced by by androgen in prostate adenocarcinoma cells
    inhibited by androgens in androgen sensitive prostate cells
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in prostatic cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS