Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PAQR7 contributors: np/ - updated : 25-11-2005
HGNC name progestin and adipoQ receptor family member VII
HGNC id 23146
Location 1p36.11      Physical location : 26.187.975 - 26.197.744
Synonym name
  • membrane progestin receptor alpha
  • mPR alpha
  • Synonym symbol(s) MPRA, mSR, 2310021M12Rik, PGLP
    DNA
    TYPE functioning gene
    STRUCTURE 9.77 kb     2 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 3023 - 346 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon moderately
    Endocrineadrenal gland    
    Reproductivefemale systemplacenta  highly
     female systemovary  moderately
     male systemprostate  moderately
     male systemtestis  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an extracellular N terminus
  • an intracellular C terminus
  • seven transmembrane domains
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to rattus Paqr7
    ortholog to murine Paqr7
    Homologene
    FAMILY
  • ADIPOR family
  • CATEGORY regulatory , receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    text integral to membrane
    basic FUNCTION
  • having potential medical significance in the diagnosis of male subfertility and a target for a new generation of fertility drugs and contraceptives
  • acting as a steroid membrane receptor
  • May be involved in oocyte maturation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS reproduction/sex
    text
  • oocyte maturation
  • PATHWAY
    metabolism
    signaling signal transduction
    G-protein coupled receptor protein signaling pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS