Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
Symbol PAPPA contributors: mct - updated : 23-09-2013
HGNC name pregnancy-associated plasma protein A, pappalysin 1
HGNC id 8602
Location 9q33.2      Physical location : 118.916.070 - 119.164.599
Synonym name
  • insulin-like growth factor-dependent IGF-binding protein 4 protease
  • differentially expressed in placenta 1
  • aspecific BCL2 ARE-binding protein 2
  • Synonym symbol(s) PAPA, DIPLA1, PAPP-A, PAPPA1, ASBABP2, IGFBP-4ase, ASBABP2
    TYPE functioning gene
    SPECIAL FEATURE opposite orientation
  • in opposite orientation with DIPAS
  • STRUCTURE 248.53 kb     22 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status confirmed
    Map cen - F36 - C9orf27 - PAPPA - qter
    Authors Daigo (99)
    Physical map
    RGS3 9q31-q33 regulator of G-protein signalling 3 FLJ31713 9q33.1 hypothetical protein FLJ31713 LOC392385 9 similar to programmed cell death 2 isoform 1; zinc finger protein Rp-8; programmed cell death 2/Rp8 homolog KIAA1952 9q33.1 KIAA1952 protein AMBP 9q32-q33 alpha-1-microglobulin/bikunin precursor KIF12 9q33.1 kinesin family member 12 COL27A1 9q33.1 collagen, type XXVII, alpha 1 ORM1 9q32 orosomucoid 1 ORM2 9q32 orosomucoid 2 AKNA 9q32 AT-hook transcription factor AKNA CIP98 9q33.1 CASK-interacting protein CIP98 ATP6V1G1 9q33.1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 1 DKFZp547P234 9q33.1 DKFZp547P234 protein LOC389786 9 LOC389786 TNFSF15 9q32 tumor necrosis factor (ligand) superfamily, member 15 LOC392386 9 similar to serine/threonine-protein kinase PRP4K; serine/threonine-protein kinase PRP4 homolog TNFSF8 9q33 tumor necrosis factor (ligand) superfamily, member 8 TNC 9q33.3 tenascin C (hexabrachion) DEC1 9q32 tenascin C (hexabrachion) C9orf27 9q31.3 chromosome 9 open reading frame 27 PAPPA 9q33.1 pregnancy-associated plasma protein A ASTN2 9q33.1 astrotactin 2 TRIM32 9q33.1 tripartite motif-containing 32 TLR4 9q32-q33 toll-like receptor 4 LOC340477 9q33.2 hypothetical LOC340477 LOC389787 9 similar to Translationally controlled tumor protein (TCTP) (p23) (Histamine-releasing factor) (HRF)
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    22 - 11025 - 1627 - 2007 1709704
    Type widely
       expressed in (based on citations)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol