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FLASH GENE
Symbol PANK4 contributors: - updated : 28-01-2006
HGNC name pantothenate kinase 4
HGNC id 19366
Location 1p36.32      Physical location : 2.439.974 - 2.458.035
Synonym name pantothenic acid kinase
Synonym symbol(s) HGNC19368, DKFZp547M242, FLJ10782
EC.number 2.7.1.33
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     18 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
text structure six exons for the core protein
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebonesubchondral  
Connectivebone   
Muscular    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • long Cterminus with DUF 89 domain
  • HOMOLOGY
    Homologene
    FAMILY pantothenate kinase family.
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • first committed step of universal CoA biosynthesis . catalyzing the phospharylation of pantothenate (vitamin B5) and derivatives
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism vitamin
    signaling
    regulatory enzyme in CoA biosynthesis
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS