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FLASH GENE
Symbol PALM3 contributors: mct - updated : 18-08-2011
HGNC name paralemmin 3
HGNC id 33274
Location 19p13.12      Physical location : 14.164.178 - 14.169.971
DNA
TYPE functioning gene
STRUCTURE 5.79 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 2260 - 673 - 2011 21187075
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY paralemmin protein family
CATEGORY adaptor
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm
text SIGIRR and PALM3 localize in cell membrane
basic FUNCTION
  • may function as adaptors that link intrinsic membrane protein to each other
  • may function as an adaptor in the LPS- Toll-like receptor 4 signaling and the interaction of SIGIRR with PALM3 may partly account for the mechanism of the negatively regulatory effect of SIGIRR
  • may be involved in the LPS-TLR4 signal transduction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PALM3 is a novel binding protein of SIGIRR
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS