basic FUNCTION
| inactivator of PAF, by removing the acetyl group at the SN-2 position |
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plays an important role during the development of brain |
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potent regulator of platelet activating factor activity, plays an important role in various physiological and pathophysiological functions including development, reproduction, inflammation, hemostasis, and apoptosis |
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PAFAh1B2 and PAFAH1B3 have profoundly different effects on brain development and interact in a significantly different manner with the Reelin signaling pathway |
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antagonistic effect of PAFAH1B2, PAFAH1B3 and NDEL1 for PAFAH1B1 binding, probably to modulate dynein functions |
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PAFAH1B2 and PAFAH1B3 expression levels affect the distribution of endosomes within the cell through interactions with the dynein regulator PAFAH1B1 |
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PAFAH Ib regulates endocytic membrane trafficking through novel mechanisms involving both PLA(2) activity and PAFAH1B1-dependent dynein function |