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FLASH GENE
Symbol PABPC4 contributors: - updated : 14-04-2004
HGNC name poly(A) binding protein, cytoplasmic 4 (inducible form)
HGNC id 8557
Location 1p34      Physical location : 40.026.484 - 40.042.521
Synonym name activated platelet protein 1
Synonym symbol(s) PABP1,APP1,IPABP
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     17 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map see OXCT2 OXCT2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticplatelet
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
four RNA binding domains RRM1 to RRM4 and a C terminal proline-rich sequence
HOMOLOGY
interspecies homolog to C.elegans y106g6h.2
homolog to rabbit app1
intraspecies homolog to PABPC1
Homologene
FAMILY
CATEGORY immunity/defense , RNA associated , antigen
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION playing a role in translation and mRNA stability
CELLULAR PROCESS nucleotide
protein, translation/synthesis
PHYSIOLOGICAL PROCESS coagulation/hemostasis
text
  • anti pathogen response
  • PATHWAY
    metabolism
    signaling
    RNA catabolism
    a component
    INTERACTION
    DNA
    RNA binding to poly (A) of mRNAs
    small molecule
    protein
    cell & other
    REGULATION
    induced by T-cell activation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS