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FLASH GENE
Symbol P2RX5 contributors: - updated : 21-07-2005
HGNC name purinergic receptor P2X, ligand-gated ion channel, 5
HGNC id 8536
Location 17p13.3      Physical location : 3.576.523 - 3.599.583
Synonym name ionotropic ATP receptor 5
Synonym symbol(s) P2X5, P2X5R
DNA
TYPE functioning gene
STRUCTURE 23.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
OR1D5 17p13.3 olfactory receptor, family 1, subfamily D, member 5 OR1D2 17p13-p12 olfactory receptor, family 1, subfamily D, member 2 OR1E3P 17p13.3 olfactory receptor, family 1, subfamily E, member 3 pseudogene OR1G1 17p13.3 olfactory receptor, family 1, subfamily G, member 1 OR1P1P 17p13.3 olfactory receptor, family 1, subfamily P, member 1 pseudogene OR1A2 17p13.3 olfactory receptor, family 1, subfamily A, member 2 OR1A1 17p13.3 olfactory receptor, family 1, subfamily A, member 1 OR1D3P 17p13.3 olfactory receptor, family 1, subfamily D, member 3 pseudogene OR3A2 17p13.3 olfactory receptor, family 3, subfamily A, member 2 OR3A1 17p13.3 olfactory receptor, family 3, subfamily A, member 1 LOC390756 17 similar to Olfactory receptor 3A4 (Olfactory receptor 17-24) (OR17-24) LOC390757 17 similar to olfactory receptor MOR157-1 OR1E1 17p13.3 olfactory receptor, family 1, subfamily E, member 1 OR3A3 17p13.3 olfactory receptor, family 3, subfamily A, member 3 OR1E2 17p13.3 olfactory receptor, family 1, subfamily E, member 2 NYD-SP20 17p13.3 testes development-related NYD-SP20 ASPA 17p13.3 aspartoacylase (aminoacylase 2, Canavan disease) TRPV3 17p13.3 transient receptor potential cation channel, subfamily V, member 3 TRPV1 17p13.3 transient receptor potential cation channel, subfamily V, member 1 CARKL 17p13 carbohydrate kinase-like CTNS 17p13.3 cystinosis, nephropathic TIP-1 17p13 Tax interaction protein 1 MGC2963 17p13.3 hypothetical protein MGC2963 P2RX5 17p13 purinergic receptor P2X, ligand-gated ion channel, 5 ITGAE 17p13 integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) GSG2 17p13 integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) HSA277841 17p13.3 ELG protein CAMKK1 17p13.3 calcium/calmodulin-dependent protein kinase kinase 1, alpha P2RX1 17p13.3 purinergic receptor P2X, ligand-gated ion channel, 1 ATP2A3 17p13.3 ATPase, Ca++ transporting, ubiquitous KIAA0399 17p13.3 KIAA0399 protein MGC32124 17p13.3 hypothetical protein MGC32124 ANKFY1 17p13.3 ankyrin repeat and FYVE domain containing 1 UBE2G1 1q42 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2206 47 422 - Le
- splicing 2150 44 397 - Le
  • lacking an in-frame segment of the coding region compared to variant 1
  • - splicing 958 19 178 - Le
  • lacking a segment in the coding region and differing in the 3' UTR compared to variant 1
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine  highly
    Lymphoid/Immunelymph node   moderately
     spleen   moderately
    Nervousbrain    
    Reproductivefemale systemuteruscervix predominantly
    Respiratoryrespiratory tractlarynx  lowly
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a transmembrane domain
  • conjugated GlycoP
    mono polymer homomer , heteromer , polymer
    HOMOLOGY
    interspecies ortholog to rattus P2rx5
    ortholog to murine P2rx5
    Homologene
    FAMILY
  • P2X receptor family
  • family of purinoceptors for ATP
  • CATEGORY receptor , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • ionotropic ATP receptor 5
  • receptor for ATP acting as a ligand gated ion channel
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text
  • ion transport
  • PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS