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FLASH GENE
Symbol OXR1 contributors: mct - updated : 23-03-2013
HGNC name oxidation resistance 1
HGNC id 15822
Location 8q23.1      Physical location : 107.282.472 - 107.764.917
Synonym name
  • putative protein product of Nbla00307
  • TBC/LysM-associated domain containing 3
  • Synonym symbol(s) Nbla00307, FLJ10125, FLJ38829, FLJ41673, FLJ42450, FLJ45656, TLDC3
    DNA
    TYPE functioning gene
    STRUCTURE 482.52 kb     16 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Physical map
    OAZIN 8q22.3 ornithine decarboxylase antizyme inhibitor LOC389679 8 similar to hypothetical protein ATP6V1C1 8q22.3 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C, isoform 1 LOC389680 8 similar to MGC39526 protein BAALC 8q22.3 brain and acute leukemia, cytoplasmic FZD6 8q22.3-q23.1 frizzled homolog 6 (Drosophila) CTHRC1 8q22.3 collagen triple helix repeat containing 1 MFTC 8q22.3 mitochondrial folate transporter/carrier DKFZP564O0463 8q22.3 DKFZP564O0463 protein TARBP2P 8q22-q24 TAR (HIV) RNA binding protein 2 pseudogene RIMS2 8q22.3 regulating synaptic membrane exocytosis 2 DCSTAMP 8q23 DC-specific transmembrane protein DPYS 8q22 dihydropyrimidinase ST7 7q31.1-q31.3 suppression of tumorigenicity 7 LOC392258 8 similar to ribosomal protein L29 LOC392259 8 similar to KIAA0779 protein ZFPM2 8q22.3-q23 zinc finger protein, multitype 2 LOC346887 8q23.1 similar to hypothetical protein FLJ30794 OXR1 8q23 oxidation resistance 1 STARS 8q23.1 striated muscle activator of Rho-dependent signaling ANGPT1 8q22.3-q23 angiopoietin 1 MGC35555 8q23.1 hypothetical protein MGC35555 LOC389681 8 similar to nuclear receptor binding factor-2; comodulator of PPAR and RXR EIF3S6 8q22-q23 eukaryotic translation initiation factor 3, subunit 6 48kDa LOC392260 8 similar to dJ753D5.2 (novel protein similar to RPS17 (40S ribosomal protein S17)) KIAA0103 8q23.2 KIAA0103 FLJ30668 8q23.2 hypothetical protein FLJ30668 TRHR 8q23 thyrotropin-releasing hormone receptor CML66 8q23 chronic myelogenous leukemia tumor antigen 66 DC6 8q23.2 DC6 protein PKHD1L1 8q23.2 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 MAPK6PS5 8q23 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 EBAG9 8q23.3 estrogen receptor binding site associated, antigen, 9 FLJ20366 8q23.2 hypothetical protein FLJ20366 LOC392261 8 similar to hypothetical protein A930017M01 KCNV1 8q22.3-q24.1 potassium channel, subfamily V, member 1 LOC392262 8 similar to laminin-binding protein
    RNA
    TRANSCRIPTS type messenger
    text exon 8, especially the region encoding a large predicted helix-turn-helix region, is the key determinant for the oxidation resistance function of the OXR1 protein (PMID: 22873401)
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 splicing 4635 94 846 - 2012 22873401
    14 splicing 4465 93 839 - 2012 22873401
  • having a distinct 5' UTR and multiple differences in the 5' coding region compared to variant 1
  • translation initiation at a different ATG compared to variant 1
  • 17 - 4716 - 873 - 2012 22873401
    16 - 4490 - 874 - 2012 22873401
    7 - 2635 - 243 - 2012 22873401
    6 - 2554 - 216 - 2012 22873401
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   moderately
    Endocrineadrenal gland   highly
    Nervousbrain   highly
    Reproductivemale systemseminal vesicles  highly
    Respiratoryrespiratory tracttrachea  predominantly
     respiratory tractlarynx  moderately
    Urinarybladder   highly
     kidney   highly
    Visualeyeretina    Mus musculusAdult
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  moderately
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Visualcone photoreceptor Mus musculusAdult
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text moderately in umbilical cord
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains

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