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FLASH GENE
Symbol OXCT2 contributors: - updated : 27-09-2004
HGNC name 3-oxoacid CoA transferase 2
HGNC id 18606
Corresponding disease
OXCT2 succinyl-CoA ketoacid CoA-transferase
Location 1p34.3      Physical location : 40.235.196 - 40.237.020
Synonym symbol(s) FKSG25, SCOT-T, FLJ00030
EC.number 2.8.3.5
DNA
TYPE functioning gene
SPECIAL FEATURE gene in gene
text located in an intron of BMP8
STRUCTURE 1.00 kb     1 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map Pter - BMP8B - OXCT2 OXCT2 - PPIE - HPCAL4 - HEYL - PABPC4 - BMP8A - MACF1 - OXCT2P - Cen
Authors Onishi (2004)
Physical map
FLJ12666 1p34.2 hypothetical protein FLJ12666 NDUFS5 1p34.2-p33 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) MACF1 1p32-p31 microtubule-actin crosslinking factor 1 BMP8A 1p34.2 bone morphogenetic protein 8a OXCT2P 1p34.2 3-oxoacid CoA transferase 2 pseudogene FLJ14351 1p34.2 hypothetical protein FLJ14351 PABPC4 1p36-p32 poly(A) binding protein, cytoplasmic 4 (inducible form) HEYL 1p34.3 hairy/enhancer-of-split related with YRPW motif-like NT5C1A 1p34.3-p33 5'-nucleotidase, cytosolic IA HPCAL4 1p34.2 hippocalcin like 4 PPIE 1p32 peptidylprolyl isomerase E (cyclophilin E) BMP8B 1p35-p32 bone morphogenetic protein 8 b(osteogenic protein 2) OXCT2 1p34 3-oxoacid CoA transferase 2 IPT 1p35.3-p34.1 3-oxoacid CoA transferase 2 MYCL1 1p34.2 v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) FLJ14490 1p34.2 hypothetical protein FLJ14490 CAP1 1p34.2 CAP, adenylate cyclase-associated protein 1 (yeast) PPT1 1p32 palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) RLF 1p32 rearranged L-myc fusion sequence LOC127391 1p34.2 similar to dJ39G22.2 (novel protein) ZMPSTE24 1p34.1-p33 zinc metalloproteinase (STE24 homolog, yeast) COL9A2 1p33-p32.3 collagen, type IX, alpha 2 LOC388621 1 similar to 60S ribosomal protein L21 LOC391028 1 similar to Csa-19 LOC64744 1p35.3-p34.1 hypothetical protein AL133206 LOC65243 1p34.2 hypothetical protein LOC65243 FLJ16030 1p34.2 FLJ16030 protein FLJ21144 1p34.2 hypothetical protein FLJ21144
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivespermatozoa
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
interspecies ortholog to murine Scot-t
Homologene
FAMILY 3-oxoacidCoA-transferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
basic FUNCTION
  • key enzyme for ketone body catabolism, transfering the CoA moiety from succinate to acetoacetate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) OXCT2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS