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FLASH GENE
Symbol OTP contributors: npt - updated : 06-11-2007
HGNC name orthopedia homeobox
HGNC id 8518
Location 5q13.3      Physical location : 76.924.537 - 76.934.522
Synonym name orthopedia homolog (Drosophila)
Synonym symbol(s) MGC3161
DNA
TYPE functioning gene
STRUCTURE 9.98 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 2702 35.1 325 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbraindiencephalonhypothalamus  
 braindiencephalonamygdala  
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a helix-turn-helix DNA binding domain
  • a homeo domain
  • HOMOLOGY
    interspecies homolog to murine Otp
    homolog to Drosophila otp
    intraspecies homolog to orthopedia gene
    Homologene
    FAMILY
  • homeodomain (HD) family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • playing key roles in the specification of cell fates
  • functioning during brain development
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS development
    text neurogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS