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FLASH GENE
Symbol OSBPL10 contributors: np/ - updated : 17-01-2007
HGNC name oxysterol binding protein-like 10
HGNC id 16395
Location 3p23      Physical location : 31.702.317 - 32.023.342
Synonym name oxysterol-binding protein-related protein 10
Synonym symbol(s) ORP10, OSBP9, FLJ20363
DNA
TYPE like-sequence
STRUCTURE 320.92 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
TGFBR2 3p22 transforming growth factor, beta receptor II (70/80kDa) LOC339896 3p23-p22.3 hypothetical protein LOC339896 LOC339897 3p22.3 similar to calponin 2; Calonin 2 LOC391524 3 similar to Thyroid hormone receptor-associated protein complex 150 kDa component (Trap150) SIMP 3p22.3 source of immunodominant MHC-associated peptides OSBPL10 3p22.3 oxysterol binding protein-like 10 LOC344787 3p22.3 similar to KIAA2033 protein KIAA0089 3p22.3 similar to KIAA2033 protein LOC391525 3 similar to 40S ribosomal protein SA (P40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associated protein MGr1-Ag) CKLFSF8 3p22.3 chemokine-like factor super family 8 CKLFSF7 3p22.3 chemokine-like factor super family 7 CKLFSF6 3p22.3 chemokine-like factor super family 6 LOC285260 3p22.3 similar to ribosomal protein L31 DNCLI1 3p22.2 dynein, cytoplasmic, light intermediate polypeptide 1 LOC391526 3 similar to Immunoglobulin-binding protein 1 (CD79a-binding protein 1) (B cell signal transduction molecule alpha 4) (Alpha 4 protein) CNOT10 3p22.3 CCR4-NOT transcription complex, subunit 10 LOC389101 3 similar to 60S ribosomal protein L23a LOC389102 3 similar to YPLR6490 LOC131405 3p22.3 similar to abnormal cell LINeage LIN-41, heterochronic gene; Drosophila dappled/ vertebrate TRipartite Motif protein related; B-box zinc finger, Filamin and NHL repeat containing protein (123.8 kD) (lin-41) CCR4 3p24 chemokine (C-C motif) receptor 4 LOC389103 3 LOC389103 GLB1 3p21.33 galactosidase, beta 1 CRTAP 3p22 cartilage associated protein KIAA0527 3p22.3 KIAA0527 protein FBXL2 3p24.3 F-box and leucine-rich repeat protein 2 UBP1 3p22.2 upstream binding protein 1 (LBP-1a) CLASP2 3p24.2-p21.33 cytoplasmic linker associated protein 2
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 4231 - 764 - -
11 - 4039 - 700 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
Visualeyeuveachoroid  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Connective    
Epithelialbarrier/liningretinal pigment epithelium (RPE)  
Lymphoid    
Nervouscentral   
cells
SystemCellPubmedSpeciesStageRna symbol
lymphoid immunelymph node
Lymphoid/ImmuneB cell
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text eye, choroid,retinalens, anterior segment
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal pleckstrin homology PH domain
  • a highly conserved OSBP-type sterol binding domain in the C terminus
  • HOMOLOGY
    Homologene
    FAMILY
  • oxysterol binding protein family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • as a regulator of cellular lipid metabolism
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS