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Symbol OPN5 contributors: mct - updated : 12-06-2012
HGNC name opsin 5
HGNC id 19992
Location 6p12.3      Physical location : 47.749.774 - 47.794.114
Synonym name
  • neuropsin
  • transmembrane protein 13
  • G protein-coupled receptor 136
  • Synonym symbol(s) HGNC19992, PGR12, GPR136, TMEM13, dJ402H5.1
    DNA
    TYPE functioning gene
    STRUCTURE 44.34 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 3496 - 354 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Nervousbrain    
     spinal cord    
    Reproductivemale systemtestis   
    Visualeyeretina    Homo sapiens
    cells
    SystemCellPubmedSpeciesStageRna symbol
    VisualMuller cell Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    seven transmembrane receptor
    HOMOLOGY
    interspecies homolog to murine Opn5
    Homologene
    FAMILY
  • rhodopsin family
  • g-protein coupled receptors
  • opsin subfamily
  • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    text integral membrane protein
    basic FUNCTION
  • rhodopsin-like receptor activity
  • first and hitherto unknown human opsin with peak sensitivity in the UV region
  • potentially triggers a UV-sensitive Gi-mediated signaling pathway in the mammalian tissues
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • capable of activating heterotrimeric G protein Gi in a UV-dependent manner
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS