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FLASH GENE
Symbol OMD contributors: - updated : 24-01-2007
HGNC name osteomodulin
HGNC id 8134
Location 9q22.31      Physical location : 95.176.527 - 95.186.836
Synonym name osteoadherin
Synonym symbol(s) OSAD, SLRR2C
DNA
TYPE functioning gene
STRUCTURE 10.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestivetooth    
Hearing/Equilibriumearinnercochlea highly
Respiratoryrespiratory tracttrachea  highly
cell lineage odontoblasts
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text odontoblasts
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 12 LRR (leucine-rich) repeats, flanked by cysteine-rich regions
    • HOMOLOGY
    Homologene
    FAMILY small leucine-rich proteoglycan (SLRP) family, class II subfamily
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION extracellular
    text dental pulp
    basic FUNCTION
  • potentially involved in biomineralization process
  • having a function in binding of osteoblasts via the alpha(V)beta(3)- integrin
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds keratan sulfate chains
    cell & other
    REGULATION
    activated by TGF beta 1 in pulpal fibroblasts and in early secretory and mature odontoblasts
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS