basic FUNCTION
| plays in cooperation with Neurogenin2 vital roles in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons  |
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required for oligodendrocytes and motor neuron specification in the spinal cord  |
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controlling the development of neural crest cells, astrocytes and oligodendrocytes, three neuroectodermal-derived cells |
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plays critical roles in oligodendrocyte and motor neuron development  |
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export of OLIG2, stimulated AKT, by from the nucleus of neural stem cell is essential for the astrocyte differentiation |
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required for the production of motor neurons and oligodendrocytes |
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repressor of neurogenesis in cells reacting to brain injury and open innovative perspectives toward evoking endogenous neuronal repair  |
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having repressor function, both sufficient and necessary to prevent neuronal differentiation and to direct subventricular zone progenitors toward astrocytic and oligodendrocytic fates |
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required for proliferation of neural progenitors and for glioma formation  |
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playing a crucial role in white matter astrocyte development, but not in the cortical gray matter astrocytes  |
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role in gliogenesis in the dorsal pallium  |
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play a role in ventral telencephalic neurogenesis  |
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marks a subpopulation of retinal progenitor cells (RPCs) that are biased toward the production of postmitotic progeny  |
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required for oligodendrocyte specification and differentiation  |
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has the ability to permeate the cell membrane without the addition of a protein transduction domain (PTD), similar to other basic helix-loop-helix transcription factors such as MYOD1 and NEUROD2  |
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OLIG2 itself had a transduction ability similar to other bHLH transcription factors  |
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functions as a prepatterning factor to direct SMARCA4 to oligodendrocyte-specific enhancers  |
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basic helix-loop-helix transcription factor necessary for oligodendroglial development and expressed continuously throughout the lineage  |
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is involved in correct formation of the prethalamus, which leads to exclusion of the EPHA3-expressing region and is crucial for proper thalamocortical axons (TCAs) formation  |