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FLASH GENE
Symbol OIT3 contributors: - updated : 24-07-2006
HGNC name oncoprotein induced transcript 3
HGNC id 29953
Location 10q22.1      Physical location : 74.653.338 - 74.692.787
Synonym name liver-specific ZP domain-containing protein
Synonym symbol(s) FLJ39116, LZP
DNA
TYPE functioning gene
STRUCTURE 40.00 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
 mouthtongue   
Lymphoid/Immunespleen    
UrinarykidneytubuleHenles loop  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three EGF-like domains
  • a ZP domain with D8C (domain with conserved eight cysteines in liver-specific ZP domain)
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION may play a role in regulating the circulating activity of cytokines as it binds to IL1, IL2 and TNF with high affinity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS