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FLASH GENE
Symbol OGFR contributors: - updated : 12-07-2005
HGNC name opioid growth factor receptor
HGNC id 15768
Location 20q13      Physical location : 61.436.176 - 61.445.351
Synonym name 7-60 protein
Synonym symbol(s) 7-60
DNA
TYPE functioning gene
STRUCTURE 9.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
motif repetitive sequence
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text five alternatively spliced variants
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
Reproductivefemale systemovary   
Skin/Tegumentskin   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Ogfr
Homologene
FAMILY
CATEGORY regulatory , receptor
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,nucleus
basic FUNCTION
  • modulating cell proliferation and tissue organization during development, cancer, angiogenesis
  • playing a crucial role in cell proliferation and wound healing
  • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS