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FLASH GENE
Symbol NXT2 contributors: - updated : 04-06-2004
HGNC name nuclear transport factor 2-like export factor 2
HGNC id 18151
Location Xq22.3      Physical location : 108.779.009 - 108.787.913
Synonym symbol(s) P15-2
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuterus   
 male systemtestis   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immunedendritic cell
cell lineage
cell lines ovarian carcinoma
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY transport
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus,nucleoplasm
intracellular,nuclear envelope
text shuttle between nucleus and cytoplasm
basic FUNCTION
  • implicated in mRNA nuclear export
  • regulating NES-containing proteins export
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA nuclear export
    small molecule
    protein binding NXF1, NXF2, NXF3, NXF5
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS