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FLASH GENE
Symbol NXF3 contributors: - updated : 12-10-2004
HGNC name nuclear RNA export factor 3
HGNC id 8073
Location Xq22-q23      Physical location : 102.330.751 - 102.348.022
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     21 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
GKP6 Xq22-q23 glycerol kinase pseudogene 6 NXF5 Xq22 nuclear RNA export factor 5 KIAA1789 Xq21 KIAA1789 protein my048 Xq22.1-q22.3 my048 protein LOC158931 Xq22.1 similar to hypothetical protein MGC15737 LOC340542 Xq22.1 hypothetical protein LOC340542 NXF2 Xq22-q23 nuclear RNA export factor 2 TMSNB Xq21.33-q22.3 thymosin, beta, identified in neuroblastoma cells LOC139707 Xq22.1 similar to checkpoint suppressor 1 NXF4 Xq22 nuclear RNA export factor 4 FLJ12969 Xq22.1-q22.3 hypothetical protein FLJ12969 GASP Xq22.1 G protein-coupled receptor-associated sorting protein LOC114928 Xq22.1 hypothetical protein BC013576 KIAA1701 Xq23 KIAA1701 protein MTND2P2 Xq22.2 NADH dehydrogenase 2 pseudogene 2 LOC286526 Xq22.2 Ras-like GTPase-like BEX1 Xq21-q23 brain expressed, X-linked 1 NXF3 Xq22-q23 nuclear RNA export factor 3 FLJ10097 Xq22.1-q22.3 hypothetical protein FLJ10097 MGC45400 Xq22.2 hypothetical protein MGC45400 LOC340543 Xq22.2 similar to hypothetical protein MGC15737 DJ79P11.1 Xq22 X-linked protein MGC23947 Xq22.1 hypothetical protein MGC23947 LOC51186 Xq22.2 pp21 homolog NGFRAP1 Xq22.1 nerve growth factor receptor (TNFRSF16) associated protein 1 RAB40A Xq22.1 RAB40A, member RAS oncogene family FLJ21174 Xq22.2 hypothetical protein FLJ21174 MGC15737 Xq22.2 hypothetical protein MGC15737 TCEAL1 Xq22.1 transcription elongation factor A (SII)-like 1 LOC139779 Xq22.2 similar to hypothetical protein FLJ38101 MORF4L2 Xq22 mortality factor 4 like 2 MGC39655 Xq22.2 hypothetical protein MGC39655 PLP1 Xq22.2 proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) RAB9B Xq22.1-q22.3 RAB9B, member RAS oncogene family LOC347393 Xq22.2 similar to bA370B6.1 (similar to histone H2B) LOC170242 Xq22.2 similar to mitochondrial carrier triple repeat 1 MGC39900 Xq22.2 hypothetical protein MGC39900 LOC158983 Xq22.2 hypothetical protein LOC158983 LOC286436 Xq22.2 hypothetical protein LOC286436 LOC392512 X similar to histone H2B-related protein LOC392513 X similar to mitochondrial carrier triple repeat 1 LOC392514 X similar to cU46H11.1 (novel protein) LOC139231 Xq22.2 hypothetical protein BC016683 ESX1L Xq22.1-q22.3 extraembryonic, spermatogenesis, homeobox 1-like
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach    
Nervousbrain    
Reproductivefemale systemovary   
 male systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one leucine-rich (LRR) repeat
  • one NTF2 domain
  • one RNA recognition motif (RRM) domain
  • RNA-binding domain is a non-canonical RNP-type domain
  • HOMOLOGY
    interspecies homolog to murine ) LOC245610
    Homologene
    FAMILY NXF family
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION nuclear mRNA export factor activity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS