basic FUNCTION
| essential for stimulating chemotaxis and morphogenesis of endothelial cells |
|
localizes with the ligand Nogo-B during VEGF and wound healing angiogenesis, mediates chemotaxis in a heterologous expression system and chemotaxis, and 3D tube formation in native endothelial cell |
|
evidence of a role for NgBR in intracellular cholesterol trafficking |
|
essential component of the dolichol monophosphate biosynthetic machinery |
|
expression of NUS1 may be essential in promoting ESR1-positive tumor cell proliferation via survivin induction in breast cancer |
|
mediates mediates pulmonary artery endothelial cells (PAECs) angiogenesis response through the modulation of AKT1/endothelial nitric oxide synthase functions, and its decreased expression is mechanistically linked to intrauterine pulmonary hypertension (IPH)-related angiogenesis defects in the developing lungs |
|
importance of NUS1 and protein glycosylation during vascular development |
|
NUS1 expression is associated with a poor prognosis of human hepatocellular carcinoma (HCC) patients |
|
is a unique receptor that promotes accumulation of prenylated RAS at the plasma membrane and promotes EGF pathways |