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FLASH GENE

Symbol

NUP210

contributors: - updated : 25-02-2005

HGNC name	nucleoporin 210kDa
HGNC id	30052

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3p25.2-p25.1      Physical location : 13.357.736 - 13.461.809
Synonym symbol(s)	GP210, POM210, FLJ22389, KIAA0906

DNA

TYPE	functioning gene
STRUCTURE	104.00 kb     40 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon   moderately   intestine small intestine     highly   stomach       lowly Lymphoid/Immune lymph node       highly   spleen       lowly   thymus       moderately Reproductive female system uterus cervix   lowly Respiratory lung       highly

cell lineage
cell lines	breast cancer, gastric tumor
fluid/secretion	blood

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

conjugated

GlycoP

mono polymer

heteromer , complex

HOMOLOGY

interspecies	homolog to murine Nup210
	homolog to rattus Pom210

Homologene

FAMILY

CATEGORY

regulatory , structural protein

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nuclear envelope,pore
text	membrane-spanning glycoprotein

basic FUNCTION

required directly or indirectly for nuclear pore formation and dilation as well as the anchoring or structural integrity of mature NPCs

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

being a major component of the nuclear pore complex

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS