protein
| binding lamin B, LAMB3 during lamina assembly binding importin alpha/beta, transportin (karyopherin KPN, TRN2) |
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interacting with SPI1 (formation of a SPI1.RanGTP.NUP153 complex) |
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interaction of NUP153 with the spindle assembly checkpoint protein MAD1L1 is important in the regulation of the spindle checkpoint  |
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DICER1 associates with NUP153(this association is detected predominantly in the cytoplasm but is also clearly distinguishable at the nuclear periphery), and NUP153 plays a crucial role in the nuclear localization of the DICER1 protein  |
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both the N-terminal and the C-terminal domain of NUP153 are directly interacting with the lamins, suggesting that NUP153 may play a role in lamin-associated diseases  |
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TP53BP1 is imported to the nucleus through the NUP153-KPNB1 interplay  |
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NUP153 binds to both SENP1 and SENP2 and does so by interacting with the unique N-terminal domain of NUP153 as well as a specific region within the C-terminal FG-rich region  |
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interaction between NUP50 and a region in the unique N-terminal region of NUP153 is critical for the nuclear pore localization of NUP50  |
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KPNB1 and NUP153 interact at the nuclear pore complex (NPC) nuclear face to form a Ran-regulated mesh that modulates NPC permeability  |
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nuclear transport receptor TNPO and the small GTPase RAN regulate the interaction of NUP153 with the membrane and, in this way, direct pore complex assembly to the nuclear envelope during interphase  |
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only NUP153 is needed for proper nuclear import of TP53BP1 and SENP1-dependent sumoylation of TP53BP1 |