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FLASH GENE
Symbol NUDT21 contributors: - updated : 06-11-2006
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 21
HGNC id 13870
Location 16q13      Physical location : 56.463.048 - 56.485.261
Synonym name
  • cleavage and polyadenylation specific factor 5
  • CPSF25
  • Synonym symbol(s) CPSF5, CFIM25, DKZp686H1588, CPSF25
    DNA
    TYPE functioning gene
    STRUCTURE 22.00 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    one nudix (Nudt/mutT) domain
    HOMOLOGY
    Homologene
    FAMILY nudix family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
    text paraspeckles
    basic FUNCTION
  • involved in the early steps in the assembly of the 3'end processing complex
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    text RNA cleavage and polyadenylation processing
    PATHWAY
    metabolism
    signaling
    a component component of the cleavage factor with CFIM68 (CPSF6)and other peptides
    INTERACTION
    DNA
    RNA RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS