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FLASH GENE
Symbol NUDCD3 contributors: mct - updated : 12-03-2015
HGNC name NudC domain containing 3
HGNC id 22208
Location 7p13      Physical location : 44.421.966 - 44.530.385
Synonym name
  • rat prolactin induced T cell protein
  • NudC-like protein
  • Synonym symbol(s) KIAA1068, NudCL
    DNA
    TYPE functioning gene
    STRUCTURE 108.42 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 4932 - 361 - 2006 16754861
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   lowly
    Nervousbrainbasal nucleicaudate nucleus  
    Reproductivefemale systemovary  lowly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a nuclear move domain
  • HOMOLOGY
    interspecies homolog to rattus prolactin induced T cell protein
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    basic FUNCTION
  • NDEL1, NUDCD3, PAFAH1B1 are critical components of cytoplasmic dynein complex
  • novel roles of PAFAH1B1, NDEL1 and NUDCD3 in the transport of mitochondria in axons
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • bind to the dynein complex, and its depletion induces degradation of dynein intermediate chain
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS