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FLASH GENE
Symbol NTSR1 contributors: - updated : 25-07-2006
HGNC name neurotensin receptor 1 (high affinity)
HGNC id 8039
Location 20q13      Physical location : 61.340.188 - 61.394.122
Synonym symbol(s) NTSR , NTR
DNA
TYPE functioning gene
STRUCTURE 53.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
ADRM1 20q13.33 adhesion regulating molecule 1 LAMA5 20q13.2-q13.3 laminin, alpha 5 RPS21 20q13.3 ribosomal protein S21 C20orf150 20q13.33 chromosome 20 open reading frame 150 C20orf151 20q13.33 chromosome 20 open reading frame 151 GATA5 20q11.21-q11.22 GATA binding protein 5 RPL7P3 20q13.33 ribosomal protein L7 pseudogene 3 C20orf166 20q13.33 chromosome 20 open reading frame 166 FLJ30313 20q13.33 hypothetical protein FLJ30313 LOC388805 20 LOC388805 FLJ32154 20q13.33 hypothetical protein FLJ32154 SLCO4A1 20q13.33 solute carrier organic anion transporter family, member 4A1 NTSR1 20q13 neurotensin receptor 1 (high affinity) LOC391261 20 similar to putative glycine-rich protein C20orf20 20q13.33 chromosome 20 open reading frame 20 OGFR 20q13 opioid growth factor receptor COL9A3 20q13.3 collagen, type IX, alpha 3 TCFL5 20q13.3 transcription factor-like 5 (basic helix-loop-helix) C20orf143 20q13.33 chromosome 20 open reading frame 143 ARF4P2 20q13.33 ADP-ribosylation factor 4 pseudogene 2 C20orf158 20q13.33 chromosome 20 open reading frame 158 DATF1 20q13.33 death associated transcription factor 1 C20orf11 20q13.33 chromosome 20 open reading frame 11 C20orf59 20q13.33 chromosome 20 open reading frame 59 LOC388806 20 hypothetical gene supported by AK128846 LOC343565 20q13.33 similar to VsaA -like protein C20orf51 20q13.33 chromosome 20 open reading frame 51
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Endocrinepancreas    
Nervousbrain    
Reproductivemale systemprostate   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
Nervouscentral   
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • may be implicated in dopamine-associated behavioral neurodegenerative and neuropsychiatric disorders
  • heterodimerization with NTSR2 may play a physiological role in the regulation of their cell surface density, and hence of their responsiveness to neurotensin, in central nevous system
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component heterodimerize with NTSR2
    INTERACTION
    DNA
    RNA
    small molecule
    protein ligand NTS
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS