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FLASH GENE
Symbol NRN1L contributors: mct - updated : 12-06-2013
HGNC name neuritin 1-like
HGNC id 29611
Location 16q22.1      Physical location : 67.918.780 - 67.920.270
Synonym name
  • candidate plasticity gene 15-2 protein
  • Synonym symbol(s) UNQ2446/PRO5725, UNQ2446, Cpg15-2
    DNA
    TYPE functioning gene
    STRUCTURE 1.49 kb     3 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 633 - 165 - 2008 18265009
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervous    predominantly Homo sapiensAdult
    Olfactory (smell)olfactory bulb   highly Homo sapiens
    Visualeyeretina  highly Homo sapiens
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Nervouscentral  predominantly Homo sapiens
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Visualbipolar cell Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , heteromer , dimer
    HOMOLOGY
    intraspecies paralog to NRN1
    Homologene
    FAMILY
  • neurotrophic factor family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text glycosylphosphatidylinositol (GPI) anchored to the cell membrane
    basic FUNCTION
  • NRN1 and NRN1L promote neurite growth and neuronal survival with similar efficacy
  • perform similar cellular functions but may play distinct roles through their cell-type- and tissue-specific transcriptional regulation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component NRN1 and NRN1L form homodimers and heterodimers with each other
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS