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FLASH GENE
Symbol NR2F6 contributors: - updated : 20-01-2005
HGNC name nuclear receptor subfamily 2, group F, member 6
HGNC id 7977
Location 19p13.1      Physical location : 17.342.694 - 17.356.151
Synonym name avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 2
Synonym symbol(s) EAR2, ERBAL2
DNA
TYPE functioning gene
STRUCTURE 13.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC284434 19p13.12 hypothetical protein LOC284434 SIN3B 19p13.11 SIN3 homolog B, transcriptional regulator (yeast) F2RL3 19p12 coagulation factor II (thrombin) receptor-like 3 VIP 6q24-q27 vasoactive intestinal peptide MGC20533 19p13.12 similar to RIKEN cDNA 2410004L22 gene (M. musculus) MYO9B 19p13.1 myosin IXB MDS032 19p13.12 uncharacterized hematopoietic stem/progenitor cells protein MDS032 FLJ22709 19p13.12 hypothetical protein FLJ22709 NR2F6 19p13.1 nuclear receptor subfamily 2, group F, member 6 MCC2 19p13 nuclear receptor subfamily 2, group F, member 6 HSPC142 19p13.12 HSPC142 protein FLJ39369 19p13.12 hypothetical protein FLJ39369 ABHD8 19p13.12 abhydrolase domain containing 8 MRPL34 19p13.1 mitochondrial ribosomal protein L33 MGC2594 19p13.12 hypothetical protein MGC2594 KIAA1623 19p13.12 KIAA1623 GTPBP3 19p13.12 GTP binding protein 3 (mitochondrial) PLVAP 19p13.2 plasmalemma vesicle associated protein BST2 19p13.2 bone marrow stromal cell antigen 2 LOC93343 19p13.12 hypothetical protein BC011840 LOC115861 19p13.12 hypothetical protein BC014127 SLC27A1 19p13.1 solute carrier family 27 (fatty acid transporter), member 1 PGLS 19p13.2 6-phosphogluconolactonase BCNP1 19p13.12 B-cell novel protein 1 FLJ22329 19p13.12 hypothetical protein FLJ22329 UNC13A 19p13.12 unc-13 homolog A (C. elegans) VCY2IP1 19p13.12 VCY2 interacting protein 1 KIAA0290
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal modulating domain
  • a central bipartite zinc finger,DNA binding domain
  • a C terminal ligand domain
  • HOMOLOGY
    Homologene
    FAMILY
  • nuclear receptor subfamily 2,group F
  • k1 steroid/thyroid receptor superfamily
  • CATEGORY protooncogene , receptor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • nuclear receptor involved in action regulation of the transcription of GNRH1 gene
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to the TGACCT repeat motif enhancing the renin gene (negative modulator of renin gene transcription )
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS