Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol NPL contributors: - updated : 03-03-2007
HGNC name N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
HGNC id 16781
Location 1q25      Physical location : 182.761.393 - 182.798.588
Synonym name
  • hypothetical protein similar to swine acylneuraminate lyase
  • chromosome 1 open reading frame 13
  • dihydrodipicolinate synthase
  • Synonym symbol(s) C112, NPL1, C1orf13, MGC149582, MGC61869
    DNA
    TYPE functioning gene
    STRUCTURE 37.00 kb     12 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 1552 - 320 - Wu
    - splicing 905 - 301 mainly expressed in human placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocyte Wu
  • having one dihydrodipicolinate synthase (DHDPS) domain, and five phosphorylation sites including three "serine" and two "threonine"
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx   highly
    Endocrineadrenal gland   highly
    Nervousspinal cord    
    Urinarykidney   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to swine acylneuraminate lyase
    Homologene
    FAMILY dihydrodipicolinate synthetase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,nucleus
    basic FUNCTION maybe involved in amino acid metabolism and transport, cell envelope biogenesis
    CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism aminoacid
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS