Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NOVA1 | contributors: mct - updated : 31-08-2016 |
HGNC name | neuro-oncological ventral antigen 1 |
HGNC id | 7886 |
|
Location | 14q12 Physical location : 26.915.089 - 27.066.960 |
Genatlas name | neuro-oncological ventral antigen 1 identified using antisera from patients with breast, and with a paraneoplastic neurologic disorder cancer, involving subcortical motor system characterized by paraneoplastic opsoclonus myoclonus ataxia |
Synonym name | |
| |
Synonym symbol(s) | NOVA-1, NOVA |
DNA |
TYPE | functioning gene |
STRUCTURE | 151.87 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
regulatory sequence | Promoter |
text structure |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| RNA binding protein with three K homology (KH) motifs |
HOMOLOGY |
interspecies | ortholog to murine Nova1 |
homolog to Drosophila ps | |
homolog to Celegans F26B1.2 |
Homologene |
FAMILY | Nova family of paraneoplasic disease antigens |
CATEGORY | RNA associated , antigen |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus,nucleolus |
basic FUNCTION | |
| |
| |
| |
| |
| |
| |
| |
| |
|
CELLULAR PROCESS | nucleotide, RNA splicing |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | nucleic |
signaling | neurotransmission |
synaptic transmission |
a component |
INTERACTION |
DNA |
RNA | binding |
small molecule |
protein | |
| |
| |
|
cell & other |
REGULATION |
inhibited by | paraneoplastic antibodies |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
|
|
|
ANIMAL & CELL MODELS |
Nova1-deficient mice (Jensen,2000) |