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Symbol NOP14 contributors: mct/npt - updated : 14-03-2017
HGNC name NOP14 nucleolar protein homolog (yeast)
HGNC id 16821
Location 4p16.3      Physical location : 2.939.663 - 2.965.118
Synonym name
  • gene near HD on 4p16.3 with homology to hypothetical S. pombe gene
  • chromosome 4 open reading frame 9
  • nucleolar protein 14
  • NOP14 homolog (S. cerevisiae)
  • nucleolar complex protein 14
  • Synonym symbol(s) C4orf9, RES4-25, NOL14
    DNA
    TYPE functioning gene
    STRUCTURE 25.45 kb     19 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    19 - 2939 97 857 - Liu (2001)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • NOP14 family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interaction with EMG1 (interaction is required for the maturation of the 18S rRNA and for 40S ribosome production) (Liu 2001)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    of PDIA3, LYAR, NOP14, NCALD and MTSS1 genes in the ovarian cancer with poor prognosis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS