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FLASH GENE
Symbol NOMO1 contributors: mct/ - updated : 29-05-2006
HGNC name NODAL modulator 1
HGNC id 30060
Location 16p13.11      Physical location : 14.927.642 - 14.990.013
Synonym name
  • pM5 protein, telomeric copy
  • pM5 protein
  • Synonym symbol(s) Nomo, PM5
    DNA
    TYPE functioning gene
    STRUCTURE 62.45 kb     31 Exon(s)
    MAPPING cloned Y linked N status provisional
    Map pter - D16S3114 - TNFRSF17 - NOMO1 - MYH11 - D16S405 - cen
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    31 - 4261 130 1222 - 2010 20538592
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
    Hearing/Equilibriumear   highly
    Reproductivefemale systemuteruscervix highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectivebone   
    Epithelialabsorptive excretorydigestive epithelium (mucosa)  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,nucleus
    text colocalizes with TMEM147 and NOMO in the endoplasmic reticulum (ER)
    basic FUNCTION
  • may antagonize NODAL signaling
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • part of Nicalin-NOMO-TMEM147 complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interaction between TMEM147, Nicalin, and NOMO
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS