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FLASH GENE
Symbol NOM1 contributors: mct - updated : 23-12-2011
HGNC name nucleolar protein with MIF4G domain 1
HGNC id 13244
Location 7q36.3      Physical location : 156.742.416 - 156.765.875
Synonym name
  • chromosome 7 open reading frame 3
  • SGD1 homolog
  • Synonym symbol(s) c7orf3, SGD1
    DNA
    TYPE functioning gene
    STRUCTURE 23.46 kb     11 Exon(s)
    motif repetitive sequence   ALU
    text structure 3' UTR that contains several Alu repeats
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 6082 96 860 - 2005 15715967
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestivepharynx   highly
    Nervousnervecranial nerve  highly
    Skin/Tegumentskin   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one MIF4G domain
  • one MA3 domain
  • HOMOLOGY
    interspecies homolog to Saccharomyces cerevisiae Sgd1p
    homolog to murine Gm1040 (76.2pc)
    Homologene
    FAMILY
  • CWC22 family
  • CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • targeting PP1 to the nucleolus
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with members of the eIF4A family of helicases
  • interaction between NOM1 and EIF4A3 (NOM1 is a missing EIF4G-like interacting partner of eIF4A3)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS