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FLASH GENE
Symbol NLE1 contributors: - updated : 24-06-2005
HGNC name notchless homolog 1 (Drosophila)
HGNC id 19889
Location 17q12      Physical location : 33.458.367 - 33.469.322
Synonym symbol(s) FLJ10458, Nle
DNA
TYPE functioning gene
STRUCTURE 10.00 kb     13 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 2591 53 485 - Stanchi
- splicing 2726 - 193 - Stanchi
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvessel   moderately
Digestivepancreas exocrine   predominantly
 stomach   moderately
Reproductivefemale systemuteruscervix highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • eight WD repeats
  • mono polymer heteromer , complex
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • acting as a signal transducer
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
  • G-protein coupled receptor protein signaling pathway
  • a component
  • heterotrimeric G-protein complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS