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FLASH GENE
Symbol NKTR contributors: mct - updated : 16-01-2008
HGNC name natural killer-tumor recognition sequence
HGNC id 7833
Location 3p23-p21      Physical location : 42.642.146 - 42.690.232
Genatlas name natural killer triggering receptor
Synonym name
  • NK-tumor recognition protein
  • natural-killer cells cyclophilin-related protein
  • Synonym symbol(s) NKCR, MGC90527, p104
    EC.number 5.2.1.8
    DNA
    TYPE functioning gene
    STRUCTURE 47.00 kb     17 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 - 7312 - 1462 - Olsen (2006)
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver   highly
    Endocrineparathyroid   highly
     thyroid   highly
    Lymphoid/Immunelymph node   highly
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophobic
    STRUCTURE
    motifs/domains
  • N terminal 58 aminoacids hydrophobic domain
  • one cyclophilin-like domain
  • HOMOLOGY
    interspecies homolog to murine Nkhr
    Homologene
    FAMILY
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION component of a putative tumor-recognition complex, involved in the function of NK cells
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS