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FLASH GENE
Symbol NKTR contributors: mct - updated : 16-01-2008
HGNC name natural killer-tumor recognition sequence
HGNC id 7833
Location 3p23-p21      Physical location : 42.642.146 - 42.690.232
Genatlas name natural killer triggering receptor
Synonym name
  • NK-tumor recognition protein
  • natural-killer cells cyclophilin-related protein
  • Synonym symbol(s) NKCR, MGC90527, p104
    EC.number 5.2.1.8
    DNA
    TYPE functioning gene
    STRUCTURE 47.00 kb     17 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Physical map
    FLJ20574 3p21.33 hypothetical protein FLJ20574 LOC391529 3 similar to SMN interacting protein1-beta OIP106 3p25.3-p24.1 similar to SMN interacting protein1-beta CCK 3p22.1-p21.3 cholecystokinin LOC391530 3 similar to SALL4B MGC26768 3p21.33 hypothetical protein MGC26768 VIPR1 3p22 vasoactive intestinal peptide receptor 1 SEC22L3 3p24.3-p22.1 SEC22 vesicle trafficking protein-like 3 (S. cerevisiae) SS18L2 3p21 synovial sarcoma translocation gene on chromosome 18-like 2 NKTR 3p23-p21 natural killer-tumor recognition sequence KIAA1190 3p21.33 hypothetical protein KIAA1190 KBTBD5 3p21.33 kelch repeat and BTB (POZ) domain containing 5 KIAA1173 3p21.33 KIAA1173 protein FLJ25467 3p21.33 hypothetical protein FLJ25467 HIG1 3p21.33 likely ortholog of mouse hypoxia induced gene 1 CCBP2 3p21.32-p21.31 chemokine binding protein 2 CYP8B1 3p22-p21.3 cytochrome P450, family 8, subfamily B, polypeptide 1 LOC389113 3 similar to Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing protein) (Single-strand binding protein) (hnRNP core protein A1) (HDP-1) (Topoisomerase-inhibitor suppressed) LOC389114 3 similar to hypothetical protein FLJ35863 LOC339903 3p21.33 hypothetical protein LOC339903 DKFZP434B172 3p21.33 DKFZP434B172 protein FLJ14566 3p21.33 hypothetical protein FLJ14566 SNRK 3p24.3-p22.1 hypothetical protein FLJ14566 FLJ10375 3p21.32 hypothetical protein FLJ10375
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 - 7312 - 1462 - Olsen (2006)
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver   highly
    Endocrineparathyroid   highly
     thyroid   highly
    Lymphoid/Immunelymph node   highly
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophobic
    STRUCTURE
    motifs/domains
  • N terminal 58 aminoacids hydrophobic domain
  • one cyclophilin-like domain
  • HOMOLOGY
    interspecies homolog to murine Nkhr
    Homologene
    FAMILY
    CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION component of a putative tumor-recognition complex, involved in the function of NK cells
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS