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FLASH GENE
Symbol NIT1 contributors: npt - updated : 15-05-2008
HGNC name nitrilase 1
HGNC id 7828
Location 1q21-q22      Physical location : 161.087.861 - 161.095.233
Synonym name nitrilase homolog 1
Synonym symbol(s) MGC57670
EC.number 3.5.-.-
DNA
TYPE functioning gene
STRUCTURE 3.00 kb     7 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1400 - 327 - Pekarsky
at the same localization
- - splicing 2400 - - - Pekarsky
at the same localization
- - splicing 1200 - - skeletal muscle, heart Pekarsky
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveliver    
Endocrinepancreas    
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumcardiac  
Muscularstriatumskeletal  
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Nit1
homolog to C.elegans NitFhit
Homologene
FAMILY
  • nitrilase superfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • catalizing the cleavage of nitriles and organic amides to the corresponding carboxylic acids and ammonia
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS