basic FUNCTION
| may play a role in neuron differentiation and development |
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first extracellular heme-binding protein found to be involved in intercellular signal transduction |
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encodes a secreted signal with neurotrophic activity in neurons |
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playing a potential role in neural cell proliferation, neuronal differentiation and inhibited differentiation of astrocytes |
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Fe(III)-protoporphyrin IX is required for its neurotrophic activity |
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may be involved in intercellular signal transduction |
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neudesin promotes neural precursor cell proliferation early in the developmental process via the MAPK and PI3 kinase pathways |
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neudesin suppresses adipogenesis in the early stage of adipocyte differentiation, suggesting that neudesin may play an important role in adipogenesis by controlling the MAPK pathway |
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potentially involved in neural development (Miyake 2009) |