Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NEK4 | contributors: mct - updated : 12-12-2012 |
HGNC name | NIMA (never in mitosis gene a)-related kinase 4 |
HGNC id | 11399 |
|
Location | 3p21.1 Physical location : 52.744.795 - 52.804.965 |
Synonym name | |
| |
Synonym symbol(s) | NRK2, STK2, pp12301, MGC33171 |
EC.number | 2.7.11.1 |
DNA |
TYPE | functioning gene |
STRUCTURE | 60.17 kb 16 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type | widely |
tissue |
|
cell lineage
cell lines
| cervical cancer cell lines, breast cancer | fluid/secretion
| |
at STAGE |
physiological period | pregnancy |
Text | placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
|
conjugated | PhosphoP |
HOMOLOGY |
interspecies | ortholog to murine Nek4 |
homolog to C.elegans Y39G10AR.4 |
intraspecies | homolog to NEK11, which is required for DNA damage-induced G2/M arrest |
Homologene |
FAMILY | |
| |
|
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytoskeleton,microtubule | |
intracellular,cytoplasm,cytoskeleton,microfilament | |
intracellular,nucleus | |
text |
basic FUNCTION | |
| |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | nucleotide, |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism
| |
Candidate gene | ||
Marker
Therapy target
|
| |
ANIMAL & CELL MODELS |