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FLASH GENE
Symbol NEGR1 contributors: npt/ - updated : 15-12-2009
HGNC name neuronal growth regulator 1
HGNC id 17302
Location 1p31.1      Physical location : 71.868.625 - 72.748.277
Synonym name
  • a kindred of IgLON
  • neurotractin
  • IgLON family member 4
  • Synonym symbol(s) KILON, MGC46680, Ntra, IGLON4, DMML2433
    DNA
    TYPE functioning gene
    STRUCTURE 879.78 kb     7 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC149224 1p31.2 similar to 40S ribosomal protein S7 (S8) RPE65 1p31 retinal pigment epithelium-specific protein 65kDa SDP35 1p31.2 cell cycle control protein SDP35 AF357533 1q31.3 thioredoxin 1 pseudogene 6 LOC388639 1 LOC388639 KIAA1365 1p31.2 densin-180 PIN1L 1p31 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1-like FLJ20331 1p31.2 hypothetical protein FLJ20331 SFRS11 1p31-p21 splicing factor, arginine/serine-rich 11 DKFZP566D1346 1p32.3-p31.3 hypothetical protein DKFZp566D1346 HHLA3 1p31.2 HERV-H LTR-associating 3 CTH 1p31 cystathionase (cystathionine gamma-lyase) LOC391048 1 similar to cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1; chord domain-containing protein 1; cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 PTGER3 1p31.2 prostaglandin E receptor 3 (subtype EP3) ZNF265 1p31 zinc finger protein 265 NEGR1 1p31.1 neuronal growth regulator 1 LOC339468 1p31.1 hypothetical protein LOC339468 LOC126811 1p31.1 similar to keratin 8; cytokeratin 8; keratin, type II cytoskeletal 8 MGC22773 1p31.1 hypothetical protein MGC22773 FPGT 1p31.1 fucose-1-phosphate guanylyltransferase CARK
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 5669 - 354 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbraindiencephalonamygdala  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an N-terminal signal sequence
  • three immunoglobulin (Ig)-like C2 domains
  • six putative glycosylation sites
  • a putative C-terminal glycosylphosphatidylinositol (GPI) anchoring signal
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine Negr1
    homolog to rattus LOC59318
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • IgLON family
  • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • neural cell adhesion, signal transduction activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS