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FLASH GENE
Symbol NDUFV3 contributors: mct - updated : 11-07-2007
HGNC name NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
HGNC id 7719
Location 21q22.3      Physical location : 44.313.377 - 44.329.772
Synonym name
  • complex I, mitochondrial respiratory chain, 10-kD subunit
  • mitochondrial NADH oxidoreductase-like protein
  • Synonym symbol(s) UOR3, CI-9KD, MIPP65
    EC.number 1.6.5.3
    DNA
    TYPE anonymous DNA segment
    SPECIAL FEATURE gene in gene
    text OBAP identical to the C-terminus of NADH dehydrogenase (ubiquinone) flavoprotein 3 (NDUFV3)
    STRUCTURE 16.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1056 - 109 - Kervinen
    - - 2151 - 473 - Kervinen
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Reproductivefemale systemuteruscervix highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    not known to contain any redox center
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    basic FUNCTION
  • NADH ubiquinone dehydrogenase (Q reductase), NADH-CoQ reductase (complex I)
  • involved in transfer of electrons from NADH to the respiratory chain (the immediate electron acceptor
  • for the enzyme is believed to be ubiquinone)
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of the complex I multi-subunit of the phosphorylation (OXPHOS)
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS