Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NDUFS3 | contributors: mct - updated : 29-08- 201 |
HGNC name | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) |
HGNC id | 7710 |
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Corresponding disease |
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Location | 11p11.2 Physical location : 47.600.561 - 47.606.115 | ||
Synonym name | |||
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Synonym symbol(s) | CI-30kD | ||
EC.number | 1.6.5.3/1.6.99.3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 5.55 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | moderately in umbilical cord |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to rattus Ndufs3 (85.9 pc) |
homolog to murine Ndufs3 (87.8 pc) |
Homologene |
FAMILY |
CATEGORY | enzyme , transport carrier |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria,inner | |
intracellular,cytoplasm,organelle,membrane | |
text | mitochondrial respiratory chain complex I |
CELLULAR PROCESS | cell life, proliferation/growth |
cell life, cell death/apoptosis | |
PHYSIOLOGICAL PROCESS | electron transport |
text | induction of apoptosis (involved in the first step in GZMA-induced cell death, by cleavage) |
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PATHWAY |
metabolism | other |
signaling |
oxygen and reactive oxygen species metabolic process |
a component |
INTERACTION |
DNA |
RNA |
small molecule | nucleotide, |
protein |
cell & other |
REGULATION |
Other | cleaved by GZMA |
ASSOCIATED DISORDERS |
corresponding disease(s) | NDUFS3 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |